Changing one’s sex

In an age where homosexuality has gained acceptance among many, there is also more consideration for changing one's sex. What does the Bible say about such surgery and practices?

I would anticipate that in the future more will be written in our circles on this topic.  At the present time, I can refer you to a report that addresses your question and related questions.  The report is “Gender Identity Disorder or Gender Dysphoria in Christian Perspective,” and was produced by the Commission on Theology and Church Relations of The Lutheran Church—Missouri Synod.  The report can certainly serve as a starting point in addressing your question.  Of special note is the “Pastoral Care for Gender Identity Confusion” section in the report.

Your question highlights yet another situation and circumstance in our day and age to which Christians can apply God’s law and gospel to all involved.